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Dysautonomia
Foundation, Inc

Recent
Publications by Dr. Felicia Axelrod
Journal
Publications
2004
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Slaugenhaupt
SA, Mull J, Leyne M, Cuajungco MP, Gill SP, Hims M, Quinero F, Axelrod FB,
Gusella JF. Rescue of a human mRNA splicing defect by the plant cytokinin kinetin. Hum. Mol. Genet. (2004); 0: 461-0.
2003
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Leyne
M, Mull J, Gill SP, Cuajungco MP, Oddoux C, Blumenfeld A, Maayan Ch, Gusella JF, Axelrod FB, Slaugenhaupt SA. (2003) Identification of the
first non-Jewish mutation in Familial Dysautonomia. Am J of Med Genet 118A:305-308.
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Cuajungco
MP, Leyne M, Gill SP, Mull J, Lu W, Zagzag D, Axelrod FB, Gusella JF, Maayan Ch, Slaugenhaupt SA. (2003) Tissue-specific
reduction in splicing efficiency of IKBKAP due to the major mutation
associated with Familial Dysautonomia.Am J Hum Genet 72:749-758.
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Brown
CM, Stemper B, Welsch G, Brys M, Axelrod FB, Hilz MJ. (2003) Orthostatic
challenge reveals impaired vascular resistance control but normal venous
pooling and capillary filtration in Familial Dysautonomia. Clinical
Science 104:163-169.
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Stemper
B, Axelrod F, Marthol H, Brown C, Brys M, Welsch G, Hilz MJ. (2003) Terminal Vessel hyperperfusion despite organ hypoperfusion in familial
dysautonomia, Clin Sci (in press).
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Bickel
A, Axelrod FB, Marthol H, Schmelz M, Hilz MJ. (2003) Sudomotor function in Familial Dysautonomia, J Neurol Neurosurg Psychiatry
75:275-279.
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Cuajungco
MP, Ando Y, Axelrod FB, Biaggioni I, Goldstein DS, Guttmacher AE, Gwinn-Hardy K, Hahn MK, Hilz MJ, Jacob G, Jens J, Kennedy WR, Liggett
SB, O'Connor DT, Peltzer SR, Robertson D, Rubin BY, Scudder Q, Smith LJ, Sonenshein GE, Svejstrup JQ, Xu Y, Slaugenhaupt SA. (2003) Hereditary
dysautonomias: current knowledge and collaborations for the future. Clin
Auton Res;13(3):180-95.
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Saini
J, Axelrod FB, Maayan C, Stringer J, Smilen SW. Urinary incontinence in familial dysautonomia. Int Urogynecol J (2003) 14:209-213.
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Kamboj
M, Axelrod FB, David R, Geffner ME, Novogroder M,Oberfield SE, Turco JH,
Maayan Ch, Kohn B. Growth hormone treatment in children with familial dysautonomia. J Pediatrics (2003) 144: 63-67.
2002
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Hilz
MJ, Axelrod FB, Haertl U, Brown CM, Stemper B. (2002) Transcranial doppler sonography during head up tilt suggests preserved central
sympathetic activation in familial dysautonomia. Journal of Neurol Neurosurg
Psychiatry;72:657-660.
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Dutsch
M, Hilz MJ, Rauhut U, Solomon J, Neundorfer B, and Axelrod FB (2002) Sympathetic pupillary dysfunction in familial dysautonomia. Journal of
Neurol Sci 195:77-83.
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Bickel
A, Axelrod FB, Schmetz M, Marthal H, Hilz MJ. (2002) Dermal microdialysis
provides evidence for hypersensitivity to noradrenaline in patients with
familial dysautonomia. J Neurol Neurosurg Psychiatry 73:299-302.
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Axelrod
FB (2002) Hereditary Sensory and Autonomic Neuropathies: Familial Dysautonomia and other HSANs. Clin Auton Res 12 Supplement 1, 2-14.
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Axelrod
FB (2002) Genetic disorders a models to understand autonomic dysfunction.
Clin Auton Res 12 Supplement 1, 1.
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Zaenglein
AL, Chang MW, Meehan SA, Axelrod FB, Orlow SJ (2002) Extensive Riga-Fede disease of the lip and tongue. Journal Amer Acad Derm 47,445-7.
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Axelrod
FB, Goldberg JD, Ye XY, Maayan C.(2002) Survival in familial dysautonomia:
Impact of early intervention. J Pediatr;141:518-23.
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Hilz
MJ, Axelrod FB, Steingrueber M, Stemper.(2002) Valsalva maneuver suggests
increased rigidity of cerebral resistance vessels in familial dysautonomia.
Clin Autonom Res.12:385-92.
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Hilz
MJ, Axelrod FB, Braeske K, Stemper. (2002) Cold pressor test demonstrates residual sympathetic cardiovascular activation in familial dysautonomia. J
Neurol Sci 196: 81-9.
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Bernardi
L, Hilz M, Stemper B, Passino C, Welsch G, Axelrod FB. (2002) Respiratory
and cerebrovascular responses to hypoxia and hypercapnia in familial dysautonomia. Am J Respir Crit Care Med. 167:141-149.
2001
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Laplaza J., Turajane, T., Axelrod, F.B. and Burke, S.W.
(2001) Non-spinal orthopaedic problems in familial dysautonomia. J of
Pediatric Orthopedics 21:229-232
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Slaugenhaupt SA, Blumenfeld A, Gill SP, Leyne M, Mull J, Cuajungco MP,
Liebert CE, Chadwick B, Idelson M, Reznik L, Robbins CM, Makalowskia I, Brownsein MJ, Krappmann D, Scheidereit C, Maayan CH, Axelrod FB , Gusella J.
(2001) Tissue-specific expression of a splicing mutation in the IKBKAP gene
causes familial dysautonomia. Am J Human Genetics 68. 598-604.
2000
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Chadwick
BP, Leyne M,Gill SP, Liebert CB, Mull J, Mezey E, Robbins CM, Pinkett HW,
Makalowska I, Maayan C, Blumenfeld A, Axelrod FB, Brownstein M, Gusella JF,
Slaugenhaupt SA. (2000) Cloning, mapping, and expression of a novel brain-specific transcript in the familial dysautonomia candidate region on
chromosome 9q31. Mammalian Genome 11.
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Axelrod,
FB, Zupanc, M, Hilz, MJ, Kramer, EL. (2000) Ictal
SPECT during autonomic crisis in familial dysautonomia. Neurology 55: 122-125.
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Hilz, M.J., and Axelrod, F.B. (2000) Quantitative sensory testing of
thermal and vibratory perception in familial dysautonomia. Clin Aut Res 10:
177-183.
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Hayek, S., Laplaza J., Axelrod, F.B. and Burke, S.W. (2000)
Spinal deformity in familial dysautonomia: Prevalence and results of brace
management. J of Bone and Joint Surgery (American), 82: 1558-1562.
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Maayan Ch, Sela, S, Axelrod FB, Kidron, D, Hochner-Celnikier D. (2000) Gynecological aspects of female familial dysautonomia. Isr Med Assoc
Journal. 2:679-683.
Textbook and Reference
Chapters
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Axelrod
FB and Maayan Ch: (1999) Familial dysautonomia. In: Gellis and Kagen's Current
Pediatric Therapy 16th Ed, FD Burg, JR Ingelfinger, ER Wald, and RA
Polin eds. WB Saunders, Philadelphia. pp 466-69.
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Axelrod FB: (1999) Familial dysautonomia. In: Autonomic Failure 4th Ed,
CJ Mathias and R Bannister, eds. Oxford University Press, New York. pp
402-418.
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Axelrod FB: (2000) Familial dysautonomia. In: Neurobase, eds. Oxford Arbor
Publishing Corp, San Diego.
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Axelrod FB and Hilz MJ: (2000 ) Familial dysautonomia. In: Handbook of
Clinical Neurolgy, vol 75, The Autonomic Nervous System, Part II.
Dysfunctions, O Appenzeller, ed. Elsevier Science BV, London. pp
143-160.
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